[HTML][HTML] Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth

AK McAllister, LC Katz, DC Lo - Neuron, 1997 - cell.com
… neurotrophins in organotypic slices of developing cortex with Trk receptor bodies (Trk–IgGs),
we found that BDNF and NT-3 oppose one another in regulating the dendritic growth of …

Exogenous BDNF, NT-3 and NT-4 differentially regulate neurite outgrowth in cultured hippocampal neurons

C Labelle, N Leclerc - Developmental Brain Research, 2000 - Elsevier
regulate neurite outgrowth. For example, in cerebral cortex, BDNF and NT-3 exerted
opposing effects on dendritic … Indeed, BDNF enhanced dendritic growth in layers 4 and 5 and …

Stage‐specific and opposing roles of BDNF, NT3 and bFGF in differentiation of purified callosal projection neurons toward cellular repair of complex circuitry

LA Catapano, P Arlotta, TA Cage… - European Journal of …, 2004 - Wiley Online Library
… transplanted or endogenous precursors/“stem cells” toward cellular repair of complex …
dendritic development that closely mimic developmental events during initial cortical development

Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis

A Ghosh, ME Greenberg - Neuron, 1995 - cell.com
… Of the growth factors that we found to be effective in signaling in cortical neurons, only bFGF,
NT-3, and BDNF … that endogenous neurotrophins may be involved in regulating neuronal …

Neurotrophins regulate dendritic growth in developing visual cortex

AK McAllister, DC Lo, LC Katz - Neuron, 1995 - cell.com
… potential role of neurotrophins was tested by treating slices of developing visual cortex with
NGF, BDNF, NT-3, … Neurosci., abstract; Ringstedt et al., 1993), we propose that endogenous

Dynamic regulation of BDNF and NT3 expression during visual system development

ES Lein, A Hohn, CJ Shatz - Journal of Comparative Neurology, 2000 - Wiley Online Library
… in the regulation of dendritic arborization in visual cortex of … BDNF is the most likely
endogenous ligand of trkB to account … synapses to control postsynaptic dendritic growth of layer 4 …

BDNF and NT3 promote thalamocortical axon growth with distinct substrate and temporal dependency

K Hanamura, A Harada… - European Journal of …, 2004 - Wiley Online Library
… In contrast, axonal outgrowth on fixed cortex was significantly enhanced by NT-3, but not by
BDNF. Semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) analysis …

Endogenous brain-derived neurotrophic factor and neurotrophin-3 antagonistically regulate survival of axotomized corticospinal neurons in vivo

KM Giehl, S Röhrig, H Bonatz, M Gutjahr… - Journal of …, 2001 - Soc Neuroscience
… by exogenous NT-3 by directly measuring cortical TrkB phosphorylation after high-dose …
This study shows that endogenous BDNF and NT-3 antagonistically regulate survival of lesioned …

… growth factor, brainderived neurotrophic factor, and neurotrophin‐3 are sorted to dense‐core vesicles and released via the regulated pathway in primary rat cortical …

YJ Wu, A Krüttgen, JC Möller, D Shine… - Journal of …, 2004 - Wiley Online Library
… , BDNF, and NT-3 in adenovirus-infected primary cortical neurons. … , BDNF, and NT-3 are
released via the regulated secretory … adenoviruses coding for NGF or BDNF, both NTs showed …

Accelerated dendritic development of rat cortical pyramidal cells and interneurons after biolistic transfection with BDNF and NT4/5

MJ Wirth, A Brün, J Grabert, S Patz, P Wahle - 2003 - journals.biologists.com
… here on dendritic growth of rat visual cortex pyramidal and interneurons overexpressing `brain-derived
neurotrophic factor' BDNF and… Opposing roles for endogenous BDNF and NT-3 in …